The TAS2R41 Polyclonal Antibody (PACO30270) is a high-quality antibody designed for research involving TAS2R41, a taste receptor responsible for detecting bitterness in the human palate. This antibody, created from rabbit immunization, is highly specific for TAS2R41 and has been validated for use in various applications such as Western blot and immunohistochemistry.TAS2R41 is a crucial receptor involved in the perception of bitter taste, playing a significant role in the sensory experience of food and beverages. Research on TAS2R41 can provide valuable insights into taste perception mechanisms, dietary preferences, and potential implications for health and nutrition.
By using the TAS2R41 Polyclonal Antibody, researchers can effectively detect and analyze TAS2R41 expression in different cell types and tissues, making it an ideal tool for studies in sensory biology, taste perception, and food science. Understanding the function of TAS2R41 can lead to advancements in taste modulation, food development, and potential therapeutic strategies targeting taste receptors.
Immunofluorescent analysis of MCF-7 cells using PACO30270 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human liver cancer using PACO30270 at dilution of 1:100.
Background:
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate α gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Synonyms:
Taste receptor type 2 member 41 (T2R41) (Taste receptor type 2 member 59) (T2R59), TAS2R41
UniProt Protein Function:
TAS2R41: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: GPCR, T2R family; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 7q35Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activityBiological Process: detection of chemical stimulus involved in sensory perception of bitter taste
