UniProt Protein Function: | TAS2R3: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: GPCR, T2R family; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 7q31.3-q32Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: detection of chemical stimulus involved in sensory perception of bitter taste; sensory perception of taste; signal transduction |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NYW6 |
NCBI GenInfo Identifier: | 114152888 |
NCBI Gene ID: | 50831 |
NCBI Accession: | Q9NYW6.3 |
UniProt Secondary Accession: | Q9NYW6,Q645W2, Q75MV6, A4D1U2 |
UniProt Related Accession: | Q9NYW6 |
Molecular Weight: | 35,915 Da |
NCBI Full Name: | Taste receptor type 2 member 3 |
NCBI Synonym Full Names: | taste 2 receptor member 3 |
NCBI Official Symbol: | TAS2R3Â Â |
NCBI Official Synonym Symbols: | T2R3Â Â |
NCBI Protein Information: | taste receptor type 2 member 3 |
UniProt Protein Name: | Taste receptor type 2 member 3 |
UniProt Synonym Protein Names: | |
Protein Family: | Taste receptor |
UniProt Gene Name: | TAS2R3Â Â |
UniProt Entry Name: | TA2R3_HUMAN |