UniProt Protein Function: | TAS2R16: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, T2R familyChromosomal Location of Human Ortholog: 7q31.1-q31.3|7q31Cellular Component: endoplasmic reticulum; plasma membrane; integral to membrane; trans-Golgi network; external side of plasma membraneMolecular Function: bitter taste receptor activity; protein bindingBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of bitter tasteDisease: Alcohol Dependence |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NYV7 |
NCBI GenInfo Identifier: | 8394395 |
NCBI Gene ID: | 50833 |
NCBI Accession: | NP_058641.1 |
UniProt Secondary Accession: | Q9NYV7 |
UniProt Related Accession: | Q9NYV7 |
Molecular Weight: | |
NCBI Full Name: | taste receptor type 2 member 16 |
NCBI Synonym Full Names: | taste 2 receptor member 16 |
NCBI Official Symbol: | TAS2R16Â Â |
NCBI Official Synonym Symbols: | BGLPT; T2R16Â Â |
NCBI Protein Information: | taste receptor type 2 member 16 |
UniProt Protein Name: | Taste receptor type 2 member 16 |
UniProt Synonym Protein Names: | |
Protein Family: | |
UniProt Gene Name: | TAS2R16Â Â |
UniProt Entry Name: | T2R16_HUMAN |