TAS2R13 Antibody (PACO42286)
- SKU:
- PACO42286
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TAS2R13 Antibody (PACO42286)
The TAS2R13 Monoclonal Antibody (PACO42286) is a valuable tool for researchers studying the TAS2R13 taste receptor, which is involved in the perception of bitter tastes. This antibody, generated in mice, has high specificity for TAS2R13 and has been validated for use in various experimental applications, including immunofluorescence and flow cytometry.TAS2R13 is a member of the TAS2R family of G protein-coupled receptors, which play a crucial role in taste perception and are involved in regulating food intake and preferences. Understanding the function of TAS2R13 can provide insights into the mechanisms underlying bitter taste perception and its impact on dietary choices and overall health.
The TAS2R13 Monoclonal Antibody is a valuable tool for researchers interested in studying the role of TAS2R13 in taste perception, as well as its potential implications for conditions such as obesity, diabetes, and eating disorders. Its high specificity and reliability make it an ideal choice for studies aiming to elucidate the complex mechanisms involved in taste perception and its impact on physiology and behavior.
| Antibody Name: | TAS2R13 Antibody (PACO42286) |
| Antibody SKU: | PACO42286 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Taste receptor type 2 member 13 protein (150-184AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of Hela cells using PACO42286 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO42286 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon tissue using PACO42286 at dilution of 1:100. |
| Background: | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate α gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Synonyms: | Taste receptor type 2 member 13 (T2R13) (Taste receptor family B member 3) (TRB3), TAS2R13 |
| UniProt Protein Function: | TAS2R13: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: GPCR, T2R family; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 12p13Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: detection of chemical stimulus involved in sensory perception of bitter taste; positive regulation of cytokinesis |
| UniProt Protein Details: | |
| NCBI Summary: | This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NYV9 |
| NCBI GenInfo Identifier: | 29839659 |
| NCBI Gene ID: | 50838 |
| NCBI Accession: | Q9NYV9.1 |
| UniProt Secondary Accession: | Q9NYV9,Q4G0I5, Q502V8, Q645X2 |
| UniProt Related Accession: | Q9NYV9 |
| Molecular Weight: | 35,118 Da |
| NCBI Full Name: | Taste receptor type 2 member 13 |
| NCBI Synonym Full Names: | taste 2 receptor member 13 |
| NCBI Official Symbol: | TAS2R13Â Â |
| NCBI Official Synonym Symbols: | TRB3; T2R13Â Â |
| NCBI Protein Information: | taste receptor type 2 member 13 |
| UniProt Protein Name: | Taste receptor type 2 member 13 |
| UniProt Synonym Protein Names: | Taste receptor family B member 3; TRB3 |
| Protein Family: | Taste receptor |
| UniProt Gene Name: | TAS2R13Â Â |
| UniProt Entry Name: | T2R13_HUMAN |
| Antibodies |
| TAS2R13 Antibody (PACO04509) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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