The TAS2R13 Polyclonal Antibody (PACO4509) is an essential tool for researchers investigating TAS2R13, a taste receptor involved in bitter taste perception. This antibody, produced through rabbit immunization, demonstrates high specificity and sensitivity towards TAS2R13 in human samples, making it a reliable option for Western blot applications. By binding to the TAS2R13 protein, this antibody allows for precise detection and analysis in various cell types, facilitating studies in taste perception and sensory research.TAS2R13, a member of the taste receptor family, plays a crucial role in detecting bitter compounds in food and beverages, contributing to our sense of taste and food selection. Understanding the function of TAS2R13 can provide insights into dietary preferences, nutritional intake, and health outcomes related to taste perception.
Research on TAS2R13 may also lead to potential applications in the food and beverage industry, as well as in the development of novel therapeutic strategies for taste-related conditions.Overall, the TAS2R13 Polyclonal Antibody (PACO4509) serves as a valuable resource for scientists studying taste receptors and their impact on human sensory perception. Its specific targeting of TAS2R13 opens up new possibilities for exploring the intricate mechanisms underlying taste sensation, potentially leading to advancements in the fields of nutrition, sensory science, and consumer preferences.
Antibody Name:
TAS2R13 Antibody
Antibody SKU:
PACO04509
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human T2R13.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TAS2R13; Taste receptor type 2 member 13; T2R13; Taste receptor family B member 3; TRB3
UniProt Protein Function:
TAS2R13: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: GPCR, T2R family; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 12p13Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: detection of chemical stimulus involved in sensory perception of bitter taste; positive regulation of cytokinesis
UniProt Protein Details:
NCBI Summary:
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]