UniProt Protein Function: | TAS2R1: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, T2R family; Membrane protein, integralChromosomal Location of Human Ortholog: 5p15Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: chemosensory behavior; detection of chemical stimulus involved in sensory perception of bitter taste |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NYW7 |
NCBI GenInfo Identifier: | 29839667 |
NCBI Gene ID: | 50834 |
NCBI Accession: | Q9NYW7.1 |
UniProt Secondary Accession: | Q9NYW7,Q646G8 |
UniProt Related Accession: | Q9NYW7 |
Molecular Weight: | 34,333 Da |
NCBI Full Name: | Taste receptor type 2 member 1 |
NCBI Synonym Full Names: | taste 2 receptor member 1 |
NCBI Official Symbol: | TAS2R1Â Â |
NCBI Official Synonym Symbols: | T2R1; TRB7Â Â |
NCBI Protein Information: | taste receptor type 2 member 1 |
UniProt Protein Name: | Taste receptor type 2 member 1 |
UniProt Synonym Protein Names: | Taste receptor family B member 7; TRB7 |
Protein Family: | Taste receptor |
UniProt Gene Name: | TAS2R1Â Â |
UniProt Entry Name: | TA2R1_HUMAN |