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Anti-TARS Antibody (CAB6993)

SKU:
CAB6993
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • Metabolism Antibodies 2 Anti-TARS Antibody CAB6993
  • Metabolism Antibodies 2 Anti-TARS Antibody CAB6993
  • Metabolism Antibodies 2 Anti-TARS Antibody CAB6993
  • Metabolism Antibodies 2 Anti-TARS Antibody CAB6993
  • Metabolism Antibodies 2 Anti-TARS Antibody CAB6993
€139 - €419
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Description

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Antibody Name:Anti-TARS Antibody
Antibody SKU:CAB6993
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TARS (NP_689508.3).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:NCI-H460, K-562, Jurkat, 293T
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TARS (NP_689508.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MFEE KASS PSGK MGGE EKPI GAGE EKQK EGGK KKNK EGSG DGGR AELN PWPE YIYT RLEM YNIL KAEH DSIL AEKA EKDS KPIK VTLP DGKQ VDAE SWKT TPYQ IACG ISQG LADN TVIA KVNN VVWD LDRP LEED CTLE LLKF EDEE AQAV YWHS SAHI MGEA MERV YGGC LCYG PPIE NGFY YDMY LEEG GVSS NDFS SLEA LCKK IIKE KQAF ERLE VKKE TLLA MF
Gene ID:6897
Uniprot:P26639
Cellular Location:Cytoplasm
Calculated MW:83kDa/86kDa
Observed MW:83kDa
Synonyms:TARS, ThrRS
Background:Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family
UniProt Protein Function:TARS: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:EC 6.1.1.3; Translation; Ligase

Chromosomal Location of Human Ortholog: 5p13.2

Cellular Component: cytoplasm; cytosol; actin cytoskeleton

Molecular Function:threonine-tRNA ligase activity; protein homodimerization activity; ATP binding

Biological Process: tRNA aminoacylation for protein translation; translation; threonyl-tRNA aminoacylation; gene expression

NCBI Summary:Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]
UniProt Code:P26639
NCBI GenInfo Identifier:60267755
NCBI Gene ID:6897
NCBI Accession:P26639.3
UniProt Related Accession:P26639
Molecular Weight:~ 83kDa
NCBI Full Name:Threonine--tRNA ligase 1, cytoplasmic
NCBI Synonym Full Names:threonyl-tRNA synthetase 1
NCBI Official Symbol:TARS1  
NCBI Official Synonym Symbols:TARS; TTD7; ThrRS  
NCBI Protein Information:threonine--tRNA ligase 1, cytoplasmic
UniProt Protein Name:Threonine--tRNA ligase, cytoplasmic
UniProt Synonym Protein Names:Threonyl-tRNA synthetase; ThrRS
UniProt Gene Name:TARS  
UniProt Entry Name:SYTC_HUMAN
Anti-TARS Antibody (CAB6993)Western blot analysis of extracts of various cell lines, using TARS Antibody (CAB6993) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Anti-TARS Antibody (CAB6993)Immunohistochemistry of paraffin-embedded mouse kidney using TARS antibody (CAB6993) at dilution of 1:100 (40x lens).
Anti-TARS Antibody (CAB6993)Immunohistochemistry of paraffin-embedded rat heart using TARS antibody (CAB6993) at dilution of 1:100 (40x lens).
Anti-TARS Antibody (CAB6993)Immunohistochemistry of paraffin-embedded mouse brain using TARS antibody (CAB6993) at dilution of 1:100 (40x lens).
Anti-TARS Antibody (CAB6993)Immunofluorescence analysis of HeLa cells using TARS antibody (CAB6993). Blue: DAPI for nuclear staining.

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