TDP-43/TARDB Rabbit Polyclonal Antibody (CAB1183)
- SKU:
- CAB1183
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TDP-43/TARDB Rabbit Polyclonal Antibody |
SKU: | CAB1183 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TDP-43/TARDBP (NP_031401.1). |
Sequence: | MSEY IRVT EDEN DEPI EIPS EDDG TVLL STVT AQFP GACG LRYR NPVS QCMR GVRL VEGI LHAP DAGW GNLV YVVN YPKD NKRK MDET DASS AVKV KRAV QKTS DLIV LGLP WKTT EQDL KEYF STFG EVLM VQVK KDLK TGHS KGFG FVRF TEYE TQVK VMSQ RHMI DGRW CDCK LPNS KQSQ DEPL RSRK VFVG RCTE DMTE DELR EFFS QYGD VMDV FIPK PFRA FAFV TFAD DQIA QSLC GEDL IIKG ISVH ISNA |
Tested Applications: | WB IP RIP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsRIP,1:20 - 1:50 |
Synonyms: | ALS10; TDP-43; TDP-43/TARDBP |
Positive Sample: | HeLa,Jurkat,SW620,HT-29,A-673,Es-2,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 45kDa |
Observed MW: | 42kDa |
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Purification Method: | Affinity purification |
Gene ID: | 23435 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |