null

TARDBP Monoclonal Antibody [Pk1B8AT] (CPAB0554)

SKU:
CPAB0554
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
Pk1B8AT
Applications:
WB
ELISA
IHC
€149
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:TARDBP Antibody
Product Sku:CPAB0554
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TARDBP mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TARDBP amino acids 1-26 purified from Ecoli.
Clone:Pk1B8AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:TARDBP antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome which produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Synonyms:TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43, ALS10.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products