TAPBP Rabbit Polyclonal Antibody (CAB1968)
- SKU:
- CAB1968
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | TAPBP Rabbit Polyclonal Antibody |
SKU: | CAB1968 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-260 of human TAPBP (NP_757345.2). |
Sequence: | VEDA SGKG LAKR PGAL LLRQ GPGE PPPR PDLD PELY LSVH DPAG ALQA AFRR YPRG APAP HCEM SRFV PLPA SAKW ASGL TPAQ NCPR ALDG AWLM VSIS SPVL SLSS LLRP QPEP QQEP VLIT MATV VLTV LTHT PAPR VRLG QDAL LDLS FAYM PPTS EAAS SLAP GPPP FGLE WRRQ HLGK GHLL LAAT PGLN GQMP AAQE GAVA FAAW DDDE PWGP WTGN GTFW LPT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | TPN; TAPA; TPSN; NGS17; TAPBP |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Single-pass type I membrane protein. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 6892 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |