TAP1 Monoclonal Antibody (CAB22769)
- SKU:
- CAB22769
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | TAP1 Monoclonal Antibody |
SKU: | CAB22769 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant funsion protein containing a sequence corresponding to amino acids 449-748 of human TAP1 (NP_000584.2). |
Sequence: | LYQM QFTQ AVEV LLSI YPRV QKAV GSSE KIFE YLDR TPRC PPSG LLTP LHLE GLVQ FQDV SFAY PNRP DVLV LQGL TFTL RPGE VTAL VGPN GSGK STVA ALLQ NLYQ PTGG QLLL DGKP LPQY EHRY LHRQ VAAV GQEP QVFG RSLQ ENIA YGLT QKPT MEEI TAAA VKSG AHSF ISGL PQGY DTEV DEAG SQLS GGQR QAVA LARA LIRK PCVL ILDD ATSA LDAN SQLQ VEQL LYES PERY SRSV LLIT QHLS LVEQ ADHI LFLE GGAI REGG THQQ LMEK KGCY WAMV QAPA DAPE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:10000 |
Synonyms: | APT1; PSF1; ABC17; ABCB2; PSF-1; RING4; TAP1N; D6S114E; TAP1*0102N; TAP1 |
Positive Sample: | A549,Mouse spleen,Mouse colon |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 81kDa |
Observed MW: | 75kDa/81kDa/75kDa |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6890 |
Clone Number: | ARC59005 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |