The TAF9B Polyclonal Antibody (CAB15845) is a valuable tool for studying the TAF9B protein, which is involved in transcriptional regulation and chromatin remodeling. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the TAF9B protein, this antibody enables researchers to detect and analyze TAF9B expression in various cell types, making it ideal for studies in molecular biology, gene regulation, and epigenetics.TAF9B is a key component of the TFIID transcription factor complex, playing a crucial role in the activation of RNA polymerase II-mediated gene transcription.
Its involvement in chromatin remodeling and transcriptional regulation makes it a valuable target for research in diverse fields, including cancer biology, developmental biology, and stem cell research. Understanding the function of TAF9B is essential for unraveling the complex mechanisms underlying gene expression and cellular differentiation, ultimately leading to new insights into disease mechanisms and potential therapeutic targets.
Product Name:
TAF9B Rabbit Polyclonal Antibody
SKU:
CAB15845
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TAF9B (NP_057059.2).
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.
Purification Method:
Affinity purification
Gene ID:
51616
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TAF9B Rabbit pAb (CAB15845) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
