TAF6L Rabbit Polyclonal Antibody (CAB14369)
- SKU:
- CAB14369
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | TAF6L Rabbit Polyclonal Antibody |
SKU: | CAB14369 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TAF6L (NP_006464.1). |
Sequence: | MSER EERR FVEI PRES VRLM AEST GLEL SDEV AALL AEDV CYRL REAT QNSS QFMK HTKR RKLT VEDF NRAL RWSS VEAV CGYG SQEA LPMR PARE GELY FPED REVN LVEL ALAT NIPK GCAE TAVR VHVS YLDG KGNL APQG SVPS AVSS LTDD LLKY YHQV TRAV LGDD PQLM KVAL QDLQ TNSK IGAL LPYF VYVV |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | PAF65A; TAF6L |
Positive Sample: | HeLa,HT-29,Jurkat,Mouse thymus,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 68kDa |
Observed MW: | 70kDa |
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.
Purification Method: | Affinity purification |
Gene ID: | 10629 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |