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TAF5L Antibody (PACO01583)

SKU:
PACO01583
Product Type:
Antibody
Reactivity:
Human
NHP - Monkey
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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Antibody Name:TAF5L Antibody
Antibody SKU:PACO01583
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human, Monkey
Immunogen:synthesized peptide derived from the Internal region of human TAF5L.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:TAF5L; PAF65B; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; PCAF-associated factor 65 beta; PAF65-beta
UniProt Protein Function:TAF5L: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Belongs to the WD repeat TAF5 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transcription factor

Chromosomal Location of Human Ortholog: 1q42.13

Molecular Function:histone acetyltransferase activity; protein binding; transcription coactivator activity; transcription factor activity

Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter

NCBI Summary:The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O75529
NCBI GenInfo Identifier:46577305
NCBI Gene ID:27097
NCBI Accession:O75529.1
UniProt Secondary Accession:O75529,Q5TDI5, Q5TDI6, Q8IW31,
UniProt Related Accession:O75529
Molecular Weight:36,991 Da
NCBI Full Name:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
NCBI Synonym Full Names:TATA-box binding protein associated factor 5 like
NCBI Official Symbol:TAF5L  
NCBI Official Synonym Symbols:PAF65B  
NCBI Protein Information:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
UniProt Protein Name:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
UniProt Synonym Protein Names:PCAF-associated factor 65 beta; PAF65-beta
Protein Family:TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor
UniProt Gene Name:TAF5L  
UniProt Entry Name:TAF5L_HUMAN

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