TAF5 Rabbit Polyclonal Antibody (CAB7221)
- SKU:
- CAB7221
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | TAF5 Rabbit Polyclonal Antibody |
SKU: | CAB7221 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 656-800 of human TAF5 (NP_008882.2). |
Sequence: | VLNG NCVR IFTG HKGP IHSL TFSP NGRF LATG ATDG RVLL WDIG HGLM VGEL KGHT DTVC SLRF SRDG EILA SGSM DNTV RLWD AIKA FEDL ETDD FTTA TGHI NLPE NSQE LLLG TYMT KSTP VVHL HFTR RNLV LAAG AYSP Q |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | TAF2D; TAFII100; TAFII-100; TAF(II)100; TAF5 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 87kDa |
Observed MW: | 100kDa |
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6877 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |