The Taf1c Polyclonal Antibody (CAB6759) is a valuable tool for researchers studying Taf1c, a protein involved in chromatin remodeling and gene transcription. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Taf1c is a key player in the regulation of gene expression and is implicated in various biological processes, making it an important target for studies in epigenetics, developmental biology, and cancer research.
By targeting Taf1c, researchers can gain valuable insights into the mechanisms underlying gene regulation and chromatin dynamics.With its specificity and reliability, the Taf1c Polyclonal Antibody (CAB6759) enables accurate detection and analysis of Taf1c protein levels in a variety of cell types. This makes it an ideal choice for researchers seeking to explore the intricate mechanisms of gene expression and chromatin remodeling in both normal and disease states.
Product Name:
TAF1C Rabbit Polyclonal Antibody
SKU:
CAB6759
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-320 of human TAF1C (NP_001230085.1).
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
9013
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TAF1C antibody (CAB6759) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
