The TAF15 Polyclonal Antibody (CAB8465) is a valuable tool for researchers studying TAF15, a key protein involved in various cellular processes including transcription regulation and RNA processing. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been extensively validated for use in Western blotting applications. By specifically binding to the TAF15 protein, researchers can effectively detect and analyze TAF15 expression in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.TAF15 is a multifunctional protein that plays a crucial role in gene expression regulation and has been implicated in the development and progression of various diseases, including cancer.
Understanding the role of TAF15 in cellular processes is essential for furthering our knowledge of gene regulation mechanisms and identifying potential therapeutic targets for diseases associated with TAF15 dysregulation.Overall, the TAF15 Polyclonal Antibody (CAB8465) is a reliable tool for researchers seeking to investigate the functions of TAF15 in both normal and disease states, providing valuable insights into the molecular mechanisms underlying biological processes and disease pathogenesis.
Product Name:
TAF15 Rabbit Polyclonal Antibody
SKU:
CAB8465
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TAF15 (NP_631961.1).
WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
Npl3; RBP56; TAF2N; TAFII68; TAF15
Positive Sample:
SKOV3,Jurkat
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
62kDa
Observed MW:
80kDa
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8148
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TAF15 Rabbit pAb (CAB8465) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
