The TADA3 Polyclonal Antibody (CAB6224) is a vital tool for researchers studying TADA3, a key component of the transcriptional coactivator complex involved in gene regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for use in Western blotting applications. By targeting the TADA3 protein, this antibody allows for the accurate detection and analysis of TADA3 expression in various cell types, making it an essential tool for investigations in the fields of molecular biology and gene transcription.TADA3 is known for its crucial role in chromatin remodeling and transcriptional activation, making it a valuable target for research into gene regulation and cellular processes.
Its involvement in gene expression modulation highlights its importance in understanding various biological pathways and its potential implications in diseases such as cancer and developmental disorders. By utilizing the TADA3 Polyclonal Antibody, researchers can gain valuable insights into the function of TADA3 and its impact on gene transcription, paving the way for innovative discoveries in the field of molecular biology.
Product Name:
TADA3 Rabbit Polyclonal Antibody
SKU:
CAB6224
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-369 of human TADA3 (NP_597814.1).
DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.
Purification Method:
Affinity purification
Gene ID:
10474
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TADA3 Rabbit pAb (CAB6224) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
