| UniProt Protein Function: | TADA2B: Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 4p16.1 Molecular Function:chromatin binding; histone acetyltransferase activity; transcription coactivator activity; transcription factor activity Biological Process: chromatin remodeling; positive regulation of histone acetylation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | TADA2B functions as a transcriptional adaptor protein that potentiates transcription through coordination of histone acetyltransferase (HAT) activity and by linking activation factors to basal transcriptional machinery (Barlev et al., 2003 [PubMed 12972612]).[supplied by OMIM, Apr 2010] |
| UniProt Code: | Q86TJ2 |
| NCBI GenInfo Identifier: | 166225686 |
| NCBI Gene ID: | 93624 |
| NCBI Accession: | Q86TJ2.2 |
| UniProt Related Accession: | Q86TJ2 |
| Molecular Weight: | 37kDa; 39kDa; 48kDa |
| NCBI Full Name: | Transcriptional adapter 2-beta |
| NCBI Synonym Full Names: | transcriptional adaptor 2B |
| NCBI Official Symbol: | TADA2BÂ Â |
| NCBI Official Synonym Symbols: | ADA2B; ADA2(beta)Â Â |
| NCBI Protein Information: | transcriptional adapter 2-beta |
| UniProt Protein Name: | Transcriptional adapter 2-beta |
| UniProt Synonym Protein Names: | ADA2-like protein beta; ADA2-beta |
| Protein Family: | Transcriptional adapter |
| UniProt Gene Name: | TADA2BÂ Â |
