Brachyury Rabbit Polyclonal Antibody (CAB16887)
- SKU:
- CAB16887
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Brachyury Rabbit Polyclonal Antibody |
SKU: | CAB16887 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | RecombinanBrachyury fusion proBrachyuryein conBrachyuryaining a sequence corresponding Brachyuryo amino acids 226-435 of human Brachyury (NP_003172.1). |
Sequence: | HKEM MEEP GDSQ QPGY SQWG WLLP GTST LCPP ANPH PQFG GALS LPST HSCD RYPT LRSH RSSP YPSP YAHR NNSP TYSD NSPA CLSM LQSH DNWS SLGM PAHP SMLP VSHN ASPP TSSS QYPS LWSV SNGA VTPG SQAA AVSN GLGA QFFR GSPA HYTP LTHP VSAP SSSG SPLY EGAA AATD IVDS QYDA AAQG RLIA SWTP VSPP SM |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | T; TFT; SAVA; Brachyury |
Positive Sample: | H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies.
Purification Method: | Affinity purification |
Gene ID: | 6862 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |