The CD300A Polyclonal Antibody (CAB16887) is a valuable tool for researchers studying CD300A, a cell surface molecule known for its role in immune regulation. This antibody, generated in rabbits, is highly specific to human samples and is validated for Western blot applications. By targeting the CD300A protein, researchers can effectively detect and analyze its presence in various cell types, making it a versatile tool for studies in immunology and cancer research.CD300A, also referred to as an immune inhibitory receptor, is essential for maintaining immune homeostasis by controlling inflammation and suppressing allergic reactions.
Its involvement in immune response modulation makes it a promising target for investigating diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD300A is crucial for the development of therapies that manipulate immune function in these pathological contexts.Overall, the CD300A Polyclonal Antibody (CAB16887) offers researchers a reliable and sensitive way to study the role of CD300A in immune regulation, providing valuable insights that could lead to the development of novel therapeutic strategies for various diseases.
Product Name:
Brachyury Rabbit Polyclonal Antibody
SKU:
CAB16887
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
RecombinanBrachyury fusion proBrachyuryein conBrachyuryaining a sequence corresponding Brachyuryo amino acids 226-435 of human Brachyury (NP_003172.1).
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies.
Purification Method:
Affinity purification
Gene ID:
6862
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts from H460 cells, using Brachyury Rabbit pAb (CAB16887) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
