The SYTL3 Polyclonal Antibody (PAC036146) is a valuable tool for researchers studying SYTL3, a protein involved in intracellular membrane trafficking and exocytosis. This antibody, produced in rabbits, exhibits high specificity for human samples and is ideal for use in Western blot applications. By binding to the SYTL3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a versatile option for studies in cell biology and neurobiology.SYTL3, also known as synaptotagmin-like protein 3, plays a crucial role in regulating membrane fusion events and neurotransmitter release in neurons. Its functions in vesicle trafficking make it a key player in synaptic transmission and neuronal communication.
Research on SYTL3 is essential for advancing our understanding of neuronal function and potential therapeutic targets for neurological disorders.With its high reactivity and specificity, the SYTL3 Polyclonal Antibody is a valuable tool for scientists investigating the intricate mechanisms of membrane trafficking and synaptic transmission. Its applications in cell biology and neuroscience make it a valuable addition to any research laboratory focused on studying intracellular signaling pathways and neuronal communication.
Western blot. All lanes: SYTL3 antibody at 5µg/ml. Lane 1: A549 whole cell lysate. Lane 2: THP-1 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 69, 61 kDa. Observed band size: 69 kDa.
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO36146 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO36146 at dilution of 1:100.
Background:
May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions.
Synonyms:
Synaptotagmin-like protein 3 (Exophilin-6), SYTL3, SLP3
UniProt Protein Function:
SYTL3: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 6q25.3Cellular Component: plasma membraneMolecular Function: calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; syntaxin bindingBiological Process: calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; vesicle fusion
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene belongs to a family of peripheral membrane proteins that play a role in vesicular trafficking. This protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
