The SYT7 Polyclonal Antibody (CAB12757) is a valuable tool for researchers studying Synaptotagmin-7 (SYT7), a key protein involved in membrane trafficking and neurotransmitter release. This antibody, produced in rabbits, is highly specific to SYT7 and is suitable for use in various applications, including Western blotting and immunofluorescence.SYT7 is a member of the synaptotagmin family of proteins, which are essential for calcium-dependent exocytosis in neurons. As a regulator of vesicle fusion and neurotransmitter release, SYT7 plays a crucial role in synaptic transmission and neuronal communication.
Dysregulation of SYT7 has been implicated in neurodegenerative disorders and cognitive impairment, making it an important target for research in neuroscience and drug development.By using the SYT7 Polyclonal Antibody, researchers can accurately detect and analyze SYT7 expression in different cell types and tissues, providing valuable insights into its function and potential therapeutic applications. This antibody is a reliable tool for advancing our understanding of SYT7 biology and its implications in neurological disorders.
Product Name:
SYT7 Rabbit Polyclonal Antibody
SKU:
CAB12757
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 38-170 of human SYT7 (NP_004191.2).
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
9066
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of SK-BR-3, using SYT7 antibody (CAB12757) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
