The Syt6 Polyclonal Antibody (CAB16171) is a valuable tool for researchers studying Synaptotagmin-6 (Syt6), a protein involved in calcium-dependent synaptic vesicle exocytosis. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Syt6 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in neuroscience and cell biology.Syt6 is known to play a crucial role in regulating neurotransmitter release and synaptic plasticity, making it a key target for research into neurological disorders and diseases.
Understanding the function of Syt6 can provide insights into how disruptions in synaptic transmission contribute to conditions such as Alzheimer's disease, Parkinson's disease, and epilepsy. By using the Syt6 Polyclonal Antibody, researchers can further unravel the mechanisms underlying these disorders and potentially identify new therapeutic targets for treatment.
Product Name:
SYT6 Rabbit Polyclonal Antibody
SKU:
CAB16171
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SYT6 (NP_001257734.1).
The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
148281
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SYT6 Rabbit pAb (CAB16171) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
