The SYT5 Polyclonal Antibody (CAB15321) is a valuable tool for researchers studying synaptotagmin-5 (SYT5), a protein involved in neurotransmitter release and synaptic plasticity in the nervous system. This polyclonal antibody, produced in rabbits, demonstrates high specificity and sensitivity for human samples, making it optimal for various applications including Western blotting.SYT5 is a critical regulator of synaptic vesicle exocytosis and is essential for proper neuronal communication and function.
Dysregulation of SYT5 has been implicated in neurological disorders such as epilepsy and schizophrenia, highlighting its importance in the field of neuroscience research. By targeting SYT5 with this antibody, researchers can accurately detect and analyze the protein in a variety of cell types, advancing our understanding of its role in synaptic transmission and potential therapeutic interventions in neurological conditions.
Product Name:
SYT5 Rabbit Polyclonal Antibody
SKU:
CAB15321
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SYT5 (NP_003171.2).
Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).
Purification Method:
Affinity purification
Gene ID:
6861
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using SYT5 Rabbit pAb (CAB15321) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
