The SYT3 Polyclonal Antibody (CAB17790) is a research tool designed for the detection of Synaptotagmin-3 (SYT3), a protein involved in synaptic vesicle trafficking and neurotransmitter release. This rabbit-derived antibody is highly specific for SYT3 in human samples and is validated for use in Western blot applications. By binding to SYT3, this antibody enables researchers to study the expression and function of this protein in various experimental settings, making it an essential tool for neurobiology and cell biology research.
SYT3 is a key player in the regulation of synaptic vesicle exocytosis, a process essential for neuronal communication and brain function. Dysregulation of SYT3 has been implicated in neurological disorders such as Alzheimer's disease and epilepsy, making it a promising target for therapeutic interventions. By using the SYT3 Polyclonal Antibody, researchers can gain insights into the mechanisms underlying synaptic transmission and potentially develop new treatments for synaptic dysfunction-related disorders.
Product Name:
SYT3 Rabbit Polyclonal Antibody
SKU:
CAB17790
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 449-590 of human SYT3 (NP_115674.1).
Predicted to enable several functions, including phospholipid binding activity; protein dimerization activity; and syntaxin binding activity. Involved in positive regulation of dendrite extension. Located in endosome.
Purification Method:
Affinity purification
Gene ID:
84258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SYT3 Rabbit pAb (CAB17790) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
