SYT12 Rabbit Polyclonal Antibody (CAB17241)
- SKU:
- CAB17241
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SYT12 Rabbit Polyclonal Antibody |
SKU: | CAB17241 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 95-200 of human SYT12 (NP_001171351.1). |
Sequence: | KGSL SIED TFES ISEL GPLE LMGR ELDL APYG TLRK SQSA DSLN SISS VSNT FGQD FTLG QVEV SMEY DTAS HTLN VAVM QGKD LLER EEAS FESC FMRV SLLP DE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | SYT11; sytXII; SYT12 |
Positive Sample: | Mouse brain |
Cellular Localization: | hippocampal mossy fiber to CA3 synapse, plasma membrane, synaptic vesicle membrane |
Calculated MW: | 47kDa |
Observed MW: | 46kDa |
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
Purification Method: | Affinity purification |
Gene ID: | 91683 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |