The SYT1 Polyclonal Antibody is a valuable tool for researchers studying the synaptic protein SYT1, which plays a crucial role in neurotransmitter release. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various research applications, such as Western blot and immunohistochemistry.SYT1, also known as synaptotagmin-1, is essential for calcium-dependent neurotransmitter release in synapses.
Dysfunction of SYT1 has been implicated in neurological disorders such as epilepsy and Alzheimer's disease, making it a key target for further investigation and drug development. By using the SYT1 Polyclonal Antibody, researchers can gain insight into the function and regulation of SYT1 in synaptic transmission, paving the way for advancements in neuroscience research.
Product Name:
SYT1 Polyclonal Antibody
SKU:
CAB24840
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SYT1(NP_005630.1).
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).
Purification Method:
Affinity purification
Gene ID:
6857
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain using SYT1 Rabbit pAb(CAB24840) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
