The Syntenin-1 Polyclonal Antibody (CAB5360) is a valuable tool for researchers studying Syntenin-1, a protein involved in various cellular processes such as cell adhesion, migration, and signaling. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Syntenin-1 is known to interact with various partner proteins and play a role in important cellular functions, including cell proliferation, invasion, and metastasis. Its involvement in these processes has led to its association with cancer progression and metastasis, making it a key target for cancer research.
By targeting Syntenin-1 with this polyclonal antibody, researchers can effectively detect and analyze the protein in different cell types, providing valuable insights into its function and potential implications in cancer biology. This antibody is an essential tool for studies in cell biology, cancer research, and drug development aimed at targeting Syntenin-1 for therapeutic intervention.
Product Name:
Syntenin Rabbit Polyclonal Antibody
SKU:
CAB5360
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human Syntenin (NP_001007068.1).
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes.
Purification Method:
Affinity purification
Gene ID:
6386
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Syntenin antibody (CAB5360) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
