Syntenin Rabbit Polyclonal Antibody (CAB5360)
- SKU:
- CAB5360
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Syntenin Rabbit Polyclonal Antibody |
SKU: | CAB5360 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human Syntenin (NP_001007068.1). |
Sequence: | MSLY PSLE DLKV DKVI QAQT AFSA NPAN PAIL SEAS APIP HDGN LYPR LYPE LSQY MGLS LNEE EIRA NVAV VSGA PLQG QLVA RPSS INYM VAPV TGND VGIR RAEI KQGI REVI LCKD QDGK IGLR LKSI DNGI FVQL VQAN SPAS LVGL RFGD QVLQ INGE NCAG WSSD KAHK VLKQ AFGE KITM TIRD RPFE RTIT MHKD STGH VGFI FKNG KITS IVKD SSAA RNGL LTEH NICE INGQ NVIG LKDS QIAD ILST |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | ST1; MDA9; SYCL; MDA-9; TACIP18; Syntenin |
Positive Sample: | HT-29,THP-1 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Melanosome, Nucleus, Peripheral membrane protein, adherens junction, cytoskeleton, cytosol, focal adhesion. |
Calculated MW: | 32kDa |
Observed MW: | 32kDa |
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes.
Purification Method: | Affinity purification |
Gene ID: | 6386 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |