The Syntaxin 12 Polyclonal Antibody (CAB8200) is a valuable tool for researchers studying the role of Syntaxin 12 in cellular processes. Syntaxin 12 is a member of the SNARE protein family that plays a key role in membrane fusion events within the endosomal system. This antibody, raised in rabbits, specifically targets Syntaxin 12 and is highly reactive with human samples.Validated for use in Western blot applications, this antibody allows for the detection and analysis of Syntaxin 12 in various cell types. Its specificity and high reactivity make it an ideal choice for studies in cell biology, molecular biology, and neuroscience.
By targeting Syntaxin 12, researchers can gain insights into the mechanisms underlying intracellular trafficking and membrane fusion processes.The study of Syntaxin 12 is of particular interest in the fields of neurobiology and cell physiology, as disruptions in membrane fusion events can lead to a variety of cellular dysfunctions. Additionally, Syntaxin 12 has been implicated in diseases such as Alzheimer's and Parkinson's, making it a potential target for therapeutic interventions. By utilizing the Syntaxin 12 Polyclonal Antibody, researchers can further explore the role of this protein in health and disease.
Product Name:
STX12 Rabbit Polyclonal Antibody
SKU:
CAB8200
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-276 of human STX12 (NP_803173.1).
Cytoplasmic side, Endomembrane system, Endosome membrane, Golgi apparatus membrane, Single-pass type IV membrane protein.
Calculated MW:
32kDa
Observed MW:
31kDa
Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in autophagosome assembly; cholesterol efflux; and protein stabilization. Located in several cellular components, including membrane raft; phagocytic vesicle; and phagophore assembly site. Part of SNARE complex. Colocalizes with BLOC-1 complex.
Purification Method:
Affinity purification
Gene ID:
23673
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STX12 antibody (CAB8200) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
