The Synembryn-A Polyclonal Antibody (CAB10393) is a high-quality research tool designed for scientists studying Synembryn-A, a protein involved in various cellular processes. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is specifically validated for use in Western blotting applications.Synembryn-A, a member of the synuclein family, is known for its role in regulating synaptic transmission and vesicle trafficking in neurons. Its function in these processes implicates it in neurological diseases such as Parkinson's and Alzheimer's. By targeting Synembryn-A with this antibody, researchers can investigate its expression levels and localization in different cell types, aiding in the understanding of its involvement in neurodegenerative disorders.
Furthermore, the availability of a reliable antibody like CAB10393 opens up opportunities for further exploration of Synembryn-A's functions in both normal physiological conditions and disease states. Its utility in various research areas, including neuroscience and neurology, makes it a valuable tool for scientists looking to uncover the mechanisms underlying synaptic dysfunction and neurodegeneration.
Product Name:
RIC8A Rabbit Polyclonal Antibody
SKU:
CAB10393
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-531 of human RIC8A (NP_001273063.1).
Predicted to enable G-protein alpha-subunit binding activity; GTPase activator activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within several processes, including basement membrane organization; gastrulation; and visual learning. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
60626
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RIC8A antibody (CAB10393) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.