The Syndecan-2 Polyclonal Antibody (CAB1810) is a key tool for researchers studying Syndecan-2, a cell surface heparan sulfate proteoglycan involved in cell adhesion, migration, and signaling. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications, including Western blotting.Syndecan-2 plays a crucial role in cell-extracellular matrix interactions, cell proliferation, and tissue repair processes. Its dysregulation has been linked to various pathological conditions, including cancer, inflammation, and fibrosis.
By targeting Syndecan-2 with this antibody, researchers can better understand the molecular mechanisms underlying these disease processes and potentially identify novel therapeutic targets.Overall, the Syndecan-2 Polyclonal Antibody (CAB1810) is a valuable tool for investigating the role of Syndecan-2 in health and disease, offering insights that could lead to the development of new treatment strategies in the future.
Product Name:
SDC2 Rabbit Polyclonal Antibody
SKU:
CAB1810
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human SDC2 (NP_002989.2).
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
Purification Method:
Affinity purification
Gene ID:
6383
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SDC2 Rabbit pAb (CAB1810) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
