CD138/Syndecan-1 Rabbit Polyclonal Antibody (CAB1235)
- SKU:
- CAB1235
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CD138/Syndecan-1 Rabbit Polyclonal Antibody |
SKU: | CAB1235 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CD138/Syndecan-1 (NP_002988.4). |
Sequence: | VATN LPPE DQDG SGDD SDNF SGSG AGAL QDIT LSQQ TPST WKDT QLLT AIPT SPEP TGLE ATAA STST LPAG EGPK EGEA VVLP EVEP GLTA REQE ATPR PRET TQLP TTHL ASTT TATT AQEP ATSH PHRD MQPG HHET STPA GPSQ ADLH TPHT EDGG PSAT ERAA EDGA SSQL PAAE GSGE QDFT FETS GENT AVVA VEPD RRNQ SPVD QGAT |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SDC; CD138; SYND1; syndecan; CD138/Syndecan-1 |
Positive Sample: | U266,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 32kDa |
Observed MW: | 32kDa/96kDa |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Purification Method: | Affinity purification |
Gene ID: | 6382 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |