CD138/Syndecan-1 Rabbit Monoclonal Antibody (CAB4174)
- SKU:
- CAB4174
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | CD138/Syndecan-1 Rabbit Monoclonal Antibody |
SKU: | CAB4174 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-254 of human Syndecan 1 (P18827). |
Sequence: | QIVA TNLP PEDQ DGSG DDSD NFSG SGAG ALQD ITLS QQTP STWK DTQL LTAI PTSP EPTG LEAT AAST STLP AGEG PKEG EAVV LPEV EPGL TARE QEAT PRPR ETTQ LPTT HLAS TTTA TTAQ EPAT SHPH RDMQ PGHH ETST PAGP SQAD LHTP HTED GGPS ATER AAED GASS QLPA AEGS GEQD FTFE TSGE NTAV VAVE PDRR NQSP VDQG ATGA SQGL LDRK EVLG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SDC; CD138; SYND1; syndecan; CD138/Syndecan-1 |
Positive Sample: | HeLa,HepG2,Mouse lung,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 32kDa |
Observed MW: | 90-100kDa/180-230kDa |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Purification Method: | Affinity purification |
Gene ID: | 6382 |
Clone Number: | ARC0918 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |