ERVFRD-1 Rabbit Polyclonal Antibody (CAB10162)
- SKU:
- CAB10162
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ERVFRD-1 Rabbit Polyclonal Antibody |
SKU: | CAB10162 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-250 of human ERVFRD-1 (NP_997465.1). |
Sequence: | AYRH PDFP LLEK AQQL LQST GSPY STNC WLCT SSST ETPG TAYP ASPR EWTS IEAE LHIS YRWD PNLK GLMR PANS LLST VKQD FPDI RQKP PIFG PIFT NINL MGIA PICV MAKR KNGT NVGT LPST VCNV TFTV DSNQ QTYQ TYTH NQFR HQPR FPKP PNIT FPQG TLLD KSSR FCQG RPSS CSTR NFWF RPAD YNQC LQIS NLSS TAEW VLLD QTRN SLFW ENKT KGAN QSQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | envFRD; UNQ6191; ERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; ERVFRD-1 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass membrane protein, Virion. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Purification Method: | Affinity purification |
Gene ID: | 405754 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |