The Synaptotagmin-11 Polyclonal Antibody (CAB8198) is a valuable tool for researchers studying Synaptotagmin-11, a key protein involved in synaptic vesicle exocytosis and neurotransmitter release. This antibody, generated in rabbits, demonstrates high specificity and sensitivity for human samples, making it an ideal choice for Western blot applications.Synaptotagmin-11 plays a crucial role in regulating calcium-dependent neurotransmitter release in neurons, making it a target of interest in neuroscience research. By detecting and analyzing Synaptotagmin-11 expression in various cell types, this antibody enables researchers to explore its function in synaptic transmission and understand its involvement in neurological disorders such as Alzheimer's disease and Parkinson's disease.
With its ability to specifically bind to Synaptotagmin-11, this polyclonal antibody provides researchers with a reliable tool for investigating the molecular mechanisms underlying synaptic communication and the potential therapeutic targets for neurological disorders. Its versatility and reliability make it a valuable asset in neurobiology and pharmacology research.
Product Name:
SYT11 Rabbit Polyclonal Antibody
SKU:
CAB8198
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 37-200 of human SYT11 (NP_689493.3).
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature.
Purification Method:
Affinity purification
Gene ID:
23208
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SYT11 antibody (CAB8198) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
