The Synaptotagmin-1 Polyclonal Antibody (CAB0992) is a valuable tool for researchers studying the protein synaptotagmin-1, which plays a crucial role in calcium-dependent neurotransmitter release in neuronal cells. This antibody is raised in rabbits and is highly reactive with human samples, making it an ideal choice for Western blot applications.Synaptotagmin-1 is an essential protein involved in synaptic vesicle exocytosis, a process critical for proper synaptic transmission in the nervous system. Dysregulation of synaptotagmin-1 has been implicated in various neurological disorders, making it a promising target for therapeutic interventions.
By using the Synaptotagmin-1 Polyclonal Antibody, researchers can accurately detect and analyze the expression levels of synaptotagmin-1 in different cell types, providing valuable insights into its function and potential implications in neurological diseases. This antibody is a valuable tool for neuroscience research and drug development efforts aimed at targeting synaptotagmin-1 for therapeutic purposes.
Product Name:
SYT1 Rabbit Polyclonal Antibody
SKU:
CAB0992
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 84-157 of human SYT1 (NP_005630.1).
This gene encodes a member of the synaptotagmin protein family. The synaptotagmins are integral membrane proteins of synaptic vesicles that serve as calcium sensors in the process of vesicular trafficking and exocytosis. The encoded protein participates in triggering neurotransmitter release at the synapse in response to calcium binding. Mutations in this gene are associated with Baker-Gordon syndrome.
Purification Method:
Affinity purification
Gene ID:
6857
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SYT1 antibody (CAB0992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
