The Synaptopodin Polyclonal Antibody (CAB8484) is a vital tool for researchers studying synaptopodin, a crucial protein found in the brain that plays a key role in synaptic plasticity. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for a variety of research applications including immunofluorescence and immunohistochemistry.Synaptopodin is known for its involvement in the formation and maintenance of dendritic spines, the tiny protrusions on neurons that are essential for synaptic transmission. Dysregulation of synaptopodin has been implicated in neurological disorders such as Alzheimer's disease and schizophrenia, making it a valuable target for further investigation.
By using the Synaptopodin Polyclonal Antibody, researchers can gain valuable insights into the function and localization of synaptopodin in various cell types, advancing our understanding of its role in synaptic plasticity and potential implications for neurological disorders. This antibody is a valuable tool for those working in neuroscience, neurology, and neurodegenerative disease research.
Product Name:
SYNPO Rabbit Polyclonal Antibody
SKU:
CAB8484
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SYNPO (NP_001159680.1).
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).
Purification Method:
Affinity purification
Gene ID:
11346
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SYNPO antibody (CAB8484) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
