The Synaptopodin Polyclonal Antibody (CAB12049) is a valuable tool for researchers studying synaptopodin, a protein critically involved in the regulation of neuronal activity and synaptic plasticity. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to synaptopodin, this antibody enables precise detection and analysis of the protein in various cellular contexts, making it an ideal choice for neuroscience and neurology research.Synaptopodin is known for its role in the maintenance of dendritic spines and synaptic function, playing a key part in neuronal communication and synaptic transmission.
Dysregulation of synaptopodin has been implicated in neurological disorders such as Alzheimer's disease, schizophrenia, and epilepsy, making it a promising target for therapeutic exploration. By understanding the function and regulation of synaptopodin, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially develop novel treatment strategies.
Product Name:
SYNPO Rabbit Polyclonal Antibody
SKU:
CAB12049
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 820-920 of human SYNPO (NP_001159680.1).
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).
Purification Method:
Affinity purification
Gene ID:
11346
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SYNPO Rabbit pAb (CAB12049) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
