The Synaptophysin Polyclonal Antibody (CAB6344) is a valuable tool for researchers studying synaptophysin, a protein located in the synaptic vesicles of neurons. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is specifically validated for use in Western blot applications.Synaptophysin is a critical protein involved in neurotransmission, playing a key role in synaptic vesicle fusion and neurotransmitter release. Research on synaptophysin is essential for understanding synaptic function, neuronal development, and synaptic plasticity, making this antibody an essential component for studies in neuroscience, neurology, and neurodegenerative diseases.
By utilizing the Synaptophysin Polyclonal Antibody (CAB6344), researchers can effectively detect and analyze the expression of synaptophysin in various cell types and tissues, providing valuable insights into synaptic activity and neuronal communication. This antibody is an indispensable tool for unraveling the complexities of the nervous system and investigating potential therapeutic targets for neurological disorders.
Product Name:
Synaptophysin Rabbit Polyclonal Antibody
SKU:
CAB6344
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 222-313 of human Synaptophysin (NP_003170.1).
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.
Purification Method:
Affinity purification
Gene ID:
6855
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Synaptophysin Rabbit pAb (CAB6344) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
