The SYN1 Polyclonal Antibody (CAB17362) is a valuable tool for researchers studying SYN1, a key protein involved in synaptic vesicle docking and neurotransmitter release. This antibody, produced in rabbits, exhibits high specificity and affinity for SYN1 in human samples, making it suitable for use in various experimental applications, including Western blotting.SYN1 is a crucial regulator of synaptic transmission in the brain, playing a vital role in maintaining proper neuronal communication and function. Dysregulation of SYN1 has been implicated in several neurological disorders, such as Alzheimer's disease, Parkinson's disease, and schizophrenia.
By utilizing the SYN1 Polyclonal Antibody, researchers can investigate the expression and function of SYN1 in different cell types and tissues, contributing to a better understanding of synaptic dysfunction and potential therapeutic targets for neurological conditions.Overall, the SYN1 Polyclonal Antibody offers a reliable and efficient tool for probing SYN1 biology in research areas related to neuroscience, neurobiology, and neurodegenerative diseases. Its specificity and sensitivity make it an essential component for studies aiming to unravel the complex mechanisms underlying synaptic function and dysfunction.
Product Name:
SYN1 Rabbit Polyclonal Antibody
SKU:
CAB17362
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SYN1. (NP_008881.2).
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
6853
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SYN1 Rabbit pAb (CAB17362) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
