The SYCP3 Polyclonal Antibody (CAB9548) is a valuable tool for researchers studying SYCP3, a protein involved in meiotic chromosome synapsis during gametogenesis. This antibody, produced through immunization of rabbits, has high specificity and sensitivity for detecting SYCP3 in human samples, making it ideal for use in Western blot applications.SYCP3 is a crucial component in the formation of the synaptonemal complex, which ensures proper alignment and pairing of homologous chromosomes during meiosis. Dysregulation of SYCP3 has been linked to meiotic defects, infertility, and genetic disorders.
By targeting SYCP3 with this antibody, researchers can investigate the role of this protein in gametogenesis and gain insights into reproductive health.This antibody is a valuable tool for scientists studying meiosis, fertility, and genetic disorders related to chromosomal abnormalities. Its high specificity and sensitivity make it a reliable option for research projects aimed at understanding the molecular mechanisms underlying meiotic chromosome synapsis and identifying potential targets for therapeutic interventions.
Product Name:
SYCP3 Rabbit Polyclonal Antibody
SKU:
CAB9548
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SYCP3 (NP_710161.1).
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
50511
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SYCP3 Rabbit pAb (CAB9548) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
