The SYCP1 Polyclonal Antibody (CAB12139) is a valuable tool for researchers studying synaptonemal complex protein 1 (SYCP1), a key protein involved in meiotic chromosome synapsis. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in various applications, including Western blotting.SYCP1 is essential for proper chromosome pairing and recombination during meiosis, making it a critical player in reproductive biology and fertility. By targeting the SYCP1 protein, this antibody enables researchers to investigate the mechanisms underlying meiotic chromosome architecture and function.
Furthermore, aberrations in SYCP1 expression or function have been linked to infertility and genetic disorders, highlighting the importance of studying this protein in reproductive health and disease. The SYCP1 Polyclonal Antibody offers researchers a reliable tool for exploring the role of SYCP1 in meiotic processes and its implications for human health.
Product Name:
SYCP1 Rabbit Polyclonal Antibody
SKU:
CAB12139
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human SYCP1 (NP_003167.2).
Enables double-stranded DNA binding activity. Involved in protein homotetramerization. Predicted to be located in synaptonemal complex. Predicted to be active in central element; male germ cell nucleus; and transverse filament.
Purification Method:
Affinity purification
Gene ID:
6847
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse testis, using SYCP1 Rabbit pAb (CAB12139) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
