The SYCE1 Polyclonal Antibody (CAB7218) is a valuable tool for researchers studying SYCE1, a protein involved in meiotic recombination during gametogenesis. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SYCE1 protein, this antibody enables precise detection and analysis in a variety of cell types.SYCE1 is essential for the proper alignment of homologous chromosomes during meiosis, ensuring genetic diversity and proper segregation of chromosomes.
Dysregulation of SYCE1 can lead to infertility and genetic disorders, making it a critical target for studies on reproductive biology and genetic diseases. By understanding the function of SYCE1, researchers can uncover new insights into fertility problems and potential therapeutic strategies.Overall, the SYCE1 Polyclonal Antibody (CAB7218) is a reliable tool for investigating the role of SYCE1 in meiotic recombination, offering valuable data for developmental biology and reproductive health research.
Product Name:
SYCE1 Rabbit Polyclonal Antibody
SKU:
CAB7218
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1).
This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
93426
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB7218) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
