The SUV420H1 Polyclonal Antibody (CAB15442) is a valuable tool for researchers studying the SUV420H1 protein, an enzyme involved in chromatin remodeling and gene regulation. This antibody, raised in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to SUV420H1, this antibody allows for the detection and analysis of the protein in various cell types, making it an ideal choice for studies in epigenetics, cancer research, and developmental biology.
SUV420H1 is a histone methyltransferase that plays a crucial role in the establishment and maintenance of heterochromatin, leading to gene silencing and genome stability. Dysregulation of SUV420H1 has been implicated in various diseases, including cancer, neurodevelopmental disorders, and aging-related conditions. By studying the function of SUV420H1, researchers can gain insights into the underlying mechanisms of these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
SUV420H1 Rabbit Polyclonal Antibody
SKU:
CAB15442
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SUV420H1 (NP_060105.3).
Sequence:
MNTS AFPS RSSR HFSK SDSF SHNN PVRF RPIK GRQE ELKE VIER FKKD EHLE KAFK CLTS GEWA RHYF LNKN KMQE KLFK EHVF IYLR MFAT DSGF EILP C
This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51111
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SUV420H1 Rabbit pAb (CAB15442) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
