The SUV39H2 Polyclonal Antibody (CAB5855) is a valuable tool for researchers studying the SUV39H2 protein, a key player in epigenetic regulation and gene silencing. This antibody, produced in rabbits, offers high reactivity with human samples and is optimized for Western blot applications. By specifically binding to SUV39H2, this antibody allows for precise detection and analysis in a variety of cell types, making it an excellent choice for studies in epigenetics, chromatin remodeling, and gene expression.SUV39H2 is a histone methyltransferase that plays a crucial role in regulating chromatin structure and gene transcription. Its involvement in epigenetic modifications has implications for various biological processes, including development, differentiation, and disease progression.
Research on SUV39H2 can provide insights into mechanisms of gene regulation and potential therapeutic targets for diseases such as cancer and neurological disorders.By utilizing the SUV39H2 Polyclonal Antibody, researchers can delve deeper into the functions and regulatory mechanisms of SUV39H2, advancing our understanding of epigenetic processes and their impact on human health. This antibody is a valuable resource for investigations into chromatin dynamics and gene expression, with the potential to contribute to the development of new therapies targeting epigenetic pathways.
Product Name:
SUV39H2 Rabbit Polyclonal Antibody
SKU:
CAB5855
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 141-350 of human SUV39H2 (NP_001180354.1).
WB,1:500 - 1:1000 ChIP,5μg antibody for 10μg-15μg of Chromatin
Synonyms:
KMT1B; SUV39H2
Positive Sample:
Mouse testis,Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Chromosome, Nucleus, centromere.
Calculated MW:
47kDa
Observed MW:
50kDa
Enables S-adenosyl-L-methionine binding activity; histone methyltransferase activity (H3-K9 specific); and zinc ion binding activity. Involved in chromatin assembly or disassembly and chromatin remodeling. Acts upstream of or within cellular response to hypoxia and negative regulation of transcription by RNA polymerase II. Located in chromatin.
Purification Method:
Affinity purification
Gene ID:
79723
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SUV39H2 Rabbit pAb (CAB5855) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
