SUV39H1 Rabbit Polyclonal Antibody (CAB3277)
- SKU:
- CAB3277
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- IP
- ChIP
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SUV39H1 Rabbit Polyclonal Antibody |
SKU: | CAB3277 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SUV39H1 (NP_003164.1). |
Sequence: | MAEN LKGC SVCC KSSW NQLQ DLCR LAKL SCPA LGIS KRNL YDFE VEYL CDYK KIRE QEYY LVKW RGYP DSES TWEP RQNL KCVR ILKQ FHKD LERE LLRR HHRS KTPR HLDP SLAN YLVQ KAKQ RRAL RRWE QELN AKRS HLGR ITVE NEVD LDGP PRAF VYIN EYRV GEGI TLNQ VAVG CECQ DCLW APTG GCCP GASL HKFA YNDQ GQVR LRAG LPIY |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | MG44; KMT1A; SUV39H; H3-K9-HMTase 1; SUV39H1 |
Positive Sample: | SH-SY5Y,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, Nucleus lamina, centromere, nucleoplasm. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6839 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |