The SUSD4 Polyclonal Antibody (PACO36606) is a valuable tool for researchers studying SUSD4, a cell surface protein involved in various biological processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the SUSD4 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it a versatile option for studies in fields such as cell biology, developmental biology, and cancer research.
SUSD4, also known as sushi domain-containing protein 4, is a multifunctional protein with implications in cell adhesion, migration, and signaling. Its diverse roles in cellular processes make it an intriguing target for investigations into development, tissue regeneration, and disease pathology. By exploring the functions of SUSD4, researchers can gain valuable insights into processes such as wound healing, organ formation, and tumor progression, paving the way for potential therapeutic interventions in the future.
Antibody Name:
SUSD4 Antibody (PACO36606)
Antibody SKU:
PACO36606
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Sushi domain-containing protein 4 protein (56-290AA)
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO36606 at dilution of 1:100.
Background:
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.
Synonyms:
Sushi domain-containing protein 4, SUSD4
UniProt Protein Function:
SUSD4: 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 1q41Cellular Component: extracellular region; integral to membraneBiological Process: complement activation, classical pathway; innate immune response; negative regulation of complement activation, alternative pathway; negative regulation of complement activation, classical pathway; regulation of complement activation
