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Survivin (Ab-117) Polyclonal Antibody (CAB24431)

SKU:
CAB24431
€259
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Description

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Product Name:Survivin (Ab-117) Polyclonal Antibody
SKU:CAB24431
Size:100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-142 of human Survivin (NP_001159.2)
Sequence:MGAP TLPP AWQP FLKD HRIS TFKN WPFL EGCA CTPE RMAE AGFI HCPT ENEP DLAQ CFFC FKEL EGWE PDDD PIEE HKKH SSGC AFLS VKKQ FEEL TLGE FLKL DRER AKNK IAKE TNNK KKEF EETA KKVR RAIE QLAA MD
Tested Applications:WB IF/ICC
Recommended Dilution:WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200
Synonyms:API4; EPR-1; Survivin(Ab-117)
Positive Sample:Rat testis
Conjugate:Unconjugated
Cellular Localization:Chromosome, Cytoplasm, Midbody, Nucleus, centromere, cytoskeleton, kinetochore, spindle.
Calculated MW:16kDa
Observed MW:16kDa

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:332
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat testis, using Survivin Rabbit pAb (CAB24431) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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